Gambaran Hasil Pemeriksaan Tes Cepat Molekuler (TCM) Metode GeneXpert Pada Sputum Pasien Tuberkulosis Dengan Diabetes Melitus (DM) Di RSUD Prof H.M.Yamin,SH

Zafira, Zafira (2025) Gambaran Hasil Pemeriksaan Tes Cepat Molekuler (TCM) Metode GeneXpert Pada Sputum Pasien Tuberkulosis Dengan Diabetes Melitus (DM) Di RSUD Prof H.M.Yamin,SH. Skripsi thesis, Universitas Perintis Indonesia.

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Abstract

Tuberculosis (TB) is a contagious infectious disease that remains a global health concern. Diabetes mellitus (DM) is known as a significant risk factor that increases an individual’s vulnerability to TB infection and complicates both diagnosis and treatment. The Molecular Rapid Test (TCM) using the GeneXpert method is a diagnostic innovation capable of detecting TB rapidly and accurately, including resistance to rifampicin. This study aimed to describe the results of the GeneXpert-based TCM examination on sputum samples from tuberculosis patients with diabetes mellitus at RSUD Prof. H. Muhammad Yamin, SH. This research is a descriptive observational study involving 25 TB patients with comorbid diabetes mellitus. The data were analyzed based on sex distribution, age group, and TCM results. Of the 25 TB-DM patients, most were male (16 people or 64%) and female (9 people or 36%). Based on age, the highest number of patients was in the elderly group (≥60 years) with 13 patients (52%). TCM results showed MTB Detected High in 12 patients (48%), Medium and Low in 5 patients each (20%), and Very Low in 3 patients (12%). The average fasting blood glucose level in TB-DM patients was high, indicating a hyperglycemic condition. Keywords: Tuberculosis, Diabetes Mellitus, GeneXpert, Molecular Rapid Test

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